Ibuprofen May Increase Heart Problems



Ibuprofen, the popular over-the-counter painkiller, may increase the odds of heart problems in patients who have osteoarthritis and are taking daily aspirin to help lower their cardiovascular risk, said Dr. K K Aggarwal, President, Heart Care Foundation of India and Editor eMedinewS.

Quoting a study published in the Annals of the Rheumatic Diseases, Dr. Aggarwal said that ibuprofen may cancel out the cardio-protective effects of daily low-dose aspirin.

In the study, use of ibuprofen and aspirin boosted arthritis patients’ one-year heart attack and stroke risk nine-fold.

Previous studies have suggested that drugs known as cox-2 inhibitors, as well as non-selective nonsteroidal anti-inflammatory drugs (NSAIDs), increase the risk of cardiovascular events. Many cox-2 inhibitors have been withdrawn from the market.

In the study investigators revisited data on more than 18,000 individuals over the age of 50 with osteoarthritis, comparing the cox-2 inhibitor lumiracoxib with either ibuprofen or naproxen. Ibuprofen and naproxen are both traditional NSAIDs.

In the study, high-risk patients taking aspirin and ibuprofen were about nine times more likely to have heart attacks and strokes over one year as those taking lumiracoxib. People taking ibuprofen were also more likely to develop congestive heart failure than those taking the cox-2 inhibitor.

The findings, are important as ibuprofen is easily available and if cardiac patients take this over-the-counter pills it may be dangerous. It can block the effect of aspirin, so there can be more heart failures, more heart attacks and more hypertension.

This is an important public health message.


  1. I see like I’m constantly looking by reason of interesting things to deliver assign to almost a variety of topics, but I manage to allow for your install develop into my reads every lifetime because you organize compelling entries that I look help to.

  2. Lenen Zonder BKR Toetsing Lenen zonder BKR toetsing stijgt in populariteit op het Internet. Veel mensen met een zogeheten BKR notatie, die toch geld willen lenen zijn op zoek naar …

  3. This is without a doubt among the more fascinating sites I have seen. It is so easy to tune out, but there is seriously still some first-rate things on the internet, and I believe your website is on the list!


Please enter your comment!
Please enter your name here