Forty percent have metabolic syndrome
Forty percent of adults over age 40 have metabolic syndrome, a constellation of obesity leading to dyslipidemia, hypertension, and insulin resistance and, thus a 10-year risk of a first heart attack event of about 17 percent. All patents with metabolic syndrome should be considered for aspirin prophylaxis. This was stated by Padma Shri and Dr B C Roy National Awardee Dr KK Aggarwal, President Heart Care Foundation of India.
Current criteria define the metabolic syndrome as the presence of any three of the following five traits:
- Abdominal obesity, defined as a waist circumference in men >35 inches and in women >32 inches.
- Serum triglycerides 150 mg/dL or drug treatment for elevated triglycerides
- Serum HDL cholesterol <40 mg/dL in men and <50 mg/dL in women or drug treatment for low HDL-C
- Blood pressure 130/85 mmHg or drug treatment for elevated blood pressure
- Fasting plasma glucose (FPG) 110 mg/dL or drug treatment for elevated blood glucose.
- Metabolic syndrome is an important risk factor for subsequent development of type 2 diabetes and/or CVD.
Thus, the key clinical implication of a diagnosis of metabolic syndrome is identification of a patient who needs aggressive lifestyle modification focused on weight reduction and increased physical activity.